Across TCGA pan-cancer cohorts, CASP16P Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated CASP16P data layer compared with 24 for mass-spec protein.
The strongest signal is observed in cholangiocarcinoma (CHOL), where higher CASP16P Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CASP16P expression acts as an unfavorable survival marker.
CHOL are the cancer types where CASP16P Mutation most reproducibly stratifies survival.