CASP16P

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CASP16P Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated CASP16P data layer compared with 24 for mass-spec protein.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher CASP16P Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CASP16P expression acts as an unfavorable survival marker.

CHOL are the cancer types where CASP16P Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CHOLOSMedianAll0.1550.725.0293view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration