Across TCGA patient cohorts, CASP16P mutation is significantly associated with the RNA expression of many other genes, with 756 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CASP16P-associated genes across cancer lineages are RNA5SP432, MIR549A, and RNA5SP198. Each is linked with CASP16P in more than 1 cancer types. Because this analysis shows association rather than direction, both CASP16P-to-partner and partner-to-CASP16P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CASP16P→partner) and Y-score (partner→CASP16P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNA5SP432 →	+0.255	+4.539	.001	.008	3	1
CESC	MIR549A →	+0.336	+5.342	<.001	.002	3	1
CESC	RNA5SP198 →	+0.277	+5.144	<.001	.003	3	1
CESC	RN7SKP263 →	+0.123	+5.569	<.001	.002	3	1
CESC	RPSAP59 →	+0.061	+5.196	<.001	.001	3	1
CESC	LINC01519 →	+0.018	+4.669	.004	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 756 associations by consensus.

Exploration

CASP16P survival (RNA) · tumor vs normal (RNA) · all CASP16P data types