Across TCGA patient cohorts, CASP16P mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CASP16P-associated genes across cancer lineages are Ku80, SETD2, and STAT3_pY705. Each is linked with CASP16P in more than 1 cancer types. Because this analysis shows association rather than direction, both CASP16P-to-partner and partner-to-CASP16P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CASP16P→partner) and Y-score (partner→CASP16P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.344	+3.183	.008	.010	3	1
UCEC	SETD2 →	-0.260	-3.000	.030	.036	3	1
UCEC	STAT3_pY705 →	-0.426	-3.169	.003	.020	3	1
UCEC	Tuberin →	+0.353	+3.009	.016	.019	3	1
UCEC	Cyclin-B1 →	+0.835	+3.169	.006	.020	3	1
UCEC	eEF2 →	+0.480	+3.169	.014	.020	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

CASP16P survival (RNA) · tumor vs normal (RNA) · all CASP16P data types