CASKP1

Across TCGA pan-cancer cohorts, CASKP1 RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated CASKP1 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher CASKP1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CASKP1 expression acts as an unfavorable survival marker.

LUSC, BRCA, and SARC are the cancer types where CASKP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	IV	0.001	0.673	.014	45	view →
BRCA	OS	Tertile	All	0.410	0.924	.003	27	view →
SARC	DFS	Tertile	All	0.188	0.519	.020	18	view →
KIRP	DFS	Tertile	All	0.709	0.926	.006	15	view →
STAD	OS	Tertile	All	0.130	0.542	.036	9	view →
KICH	OS	Tertile	All	0.844	0.965	.049	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CASKP1–LUSC (OS)

Open the LUSC breakdown →