CASKIN2

Across TCGA patient cohorts, CASKIN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,540 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CASKIN2-associated proteins across cancer lineages are MAN2A1, MTDH, and FNDC3B. Each is linked with CASKIN2 in more than 5 cancer types. Because this analysis shows association rather than direction, both CASKIN2-to-partner and partner-to-CASKIN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CASKIN2 versus MAN2A1 in GBM, with a Pearson correlation of -0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CASKIN2→partner) and Y-score (partner→CASKIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MAN2A1 →	-0.374	-0.388	<.001	<.001	3	6
LSCC	MTDH →	-0.310	-0.616	<.001	<.001	3	5
GBM	FNDC3B →	-0.381	-0.328	<.001	<.001	3	5
LSCC	MTA1 →	+0.296	+0.544	<.001	<.001	3	5
LUAD	DOCK2_S1706 →	-0.979	-0.500	<.001	<.001	3	5
LSCC	DOCK8_S904 →	-0.554	-0.579	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,540 associations by consensus.

CASKIN2 vs MAN2A1 — GBM

Explore this scatter interactively →