CASKIN2

Across TCGA patient cohorts, CASKIN2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,389 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CASKIN2-associated genes across cancer lineages are CRYAB, SPARCL1, and DACT3. Each is linked with CASKIN2 in more than 4 cancer types. Because this analysis shows association rather than direction, both CASKIN2-to-partner and partner-to-CASKIN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CASKIN2 versus CRYAB in HNSC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CASKIN2→partner) and Y-score (partner→CASKIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CRYAB →	+1.186	+0.136	<.001	.003	3	5
UCEC	SPARCL1 →	+1.358	+0.262	<.001	<.001	3	4
UCEC	DACT3 →	+0.986	+0.288	<.001	<.001	3	4
GBM	LIMS2 →	+0.989	+0.166	.001	.003	3	4
UCEC	GUCY1A2 →	+0.994	+0.225	<.001	<.001	3	4
OV	DCN →	+1.263	+0.308	.004	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,389 associations by consensus.

CASKIN2 vs CRYAB — HNSC

Explore this scatter interactively →