CASKIN1

Across TCGA patient cohorts, CASKIN1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,573 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CASKIN1-associated genes across cancer lineages are ATP6V1A, IFIT2, and SECISBP2L. Each is linked with CASKIN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CASKIN1-to-partner and partner-to-CASKIN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CASKIN1 versus ATP6V1A in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CASKIN1→partner) and Y-score (partner→CASKIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ATP6V1A →	+0.626	+0.804	.009	.001	3	2
BRCA	IFIT2 →	+1.317	+0.709	<.001	<.001	3	2
BRCA	SECISBP2L →	+0.621	+0.600	.006	.005	3	2
BRCA	PLPBP →	+1.120	+1.055	.004	<.001	3	2
BRCA	IFIT5 →	+0.835	+0.690	.001	.001	3	2
BRCA	BAG4 →	+1.159	+0.809	.004	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,573 associations by consensus.

CASKIN1 vs ATP6V1A — BRCA

Explore this scatter interactively →