CASK

Across TCGA cell cohorts, CASK RNA expression is significantly associated with the go_rna of many other GO terms, with 3,833 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CASK-associated GO terms across cancer lineages are GDP metabolic process, Growth hormone secretion, and Copper ion export. Each is linked with CASK in more than 13 cancer types. Because this analysis shows association rather than direction, both CASK-to-partner and partner-to-CASK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GDP metabolic process grouped by CASK-low versus CASK-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CASK→partner) and Y-score (partner→CASK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	GDP metabolic process →	+0.173	+1.102	<.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Growth hormone secretion →	+0.139	+1.134	<.001	<.001	3	12
URINARY_TRACT	Copper ion export →	-0.218	-1.342	.001	<.001	2	10
KIDNEY	Peptidyl-serine phosphorylation →	+0.085	+1.025	.001	.003	3	9
KIDNEY	Peptidyl-serine modification →	+0.094	+1.104	.001	.006	3	9
STOMACH	Atrioventricular valve morphogenesis →	+0.099	+0.921	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,833 associations by consensus.

GDP metabolic process by CASK expression — URINARY_TRACT

Explore this box plot interactively →