CASD1

Across TCGA cell cohorts, CASD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,414 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CASD1-associated GO terms across cancer lineages are Positive regulation of double-strand break repair, Centriole-centriole cohesion, and Late viral transcription. Each is linked with CASD1 in more than 11 cancer types. Because this analysis shows association rather than direction, both CASD1-to-partner and partner-to-CASD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair grouped by CASD1-low versus CASD1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CASD1→partner) and Y-score (partner→CASD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of double-strand break repair →	+0.072	+0.937	<.001	<.001	3	12
LUNG_SCLC	Centriole-centriole cohesion →	+0.098	+0.920	<.001	.004	3	11
LUNG_SCLC	Late viral transcription →	+0.129	+0.737	<.001	.009	3	11
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication maintenance of fidelity →	+0.095	+0.702	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Positive regulation of DNA recombination →	+0.069	+0.765	<.001	<.001	3	11
LUNG_SCLC	Positive regulation of DNA metabolic process →	+0.060	+0.981	<.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,414 associations by consensus.

Positive regulation of double-strand break repair by CASD1 expression — LUNG_SCLC

Explore this box plot interactively →