CASC17

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, CASC17 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of CASC17’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CASC17 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CASC17 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

HNSC and KIRC are the cancer types where CASC17 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CASC17 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
HNSCAllAll+0.015.0084view →
KIRCFemaleAll−0.006.0371view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

CASC17–HNSC

Tumor-vs-normal expression box plot for CASC17 RNA in HNSC.

Open the HNSC breakdown →

Exploration