CASC11

Across TCGA pan-cancer cohorts, CASC11 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated CASC11 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher CASC11 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CASC11 expression acts as an unfavorable survival marker, although some lineages such as LGG and READ show a favorable association.

ACC, UCEC, and KIRC are the cancer types where CASC11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.412	0.823	<.001	113	view →
UCEC	DFS	Tertile	III,IV	0.700	0.879	<.001	62	view →
KIRC	OS	Median	All	0.550	0.691	.001	61	view →
PAAD	DFS	Quartile	All	0.360	0.603	<.001	49	view →
LGG	DFS	Median	All	0.811	0.672	<.001	49	view →
READ	OS	Tertile	III,IV	0.813	0.296	.002	37	view →
KIRP	DFS	Median	All	0.848	0.957	<.001	26	view →
THCA	DFS	Quartile	IV	0.457	0.803	.005	24	view →
DLBC	DFS	Median	IV	0.128	1.000	.017	19	view →
SKCM	DFS	Quartile	All	0.393	0.176	.002	18	view →
LIHC	OS	Tertile	All	0.615	0.797	.004	18	view →
MESO	OS	Quartile	III,IV	0.722	0.493	.005	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

CASC11–ACC (OS)

Open the ACC breakdown →