CARS1P1

Across TCGA pan-cancer cohorts, CARS1P1 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated CARS1P1 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher CARS1P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CARS1P1 expression acts as an unfavorable survival marker, although some lineages such as LAML and LGG show a favorable association.

READ, PAAD, and LAML are the cancer types where CARS1P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Tertile	II,III,IV	0.200	0.827	<.001	78	view →
PAAD	DFS	Tertile	All	0.068	0.484	<.001	72	view →
LAML	DFS	Quartile	All	0.595	0.306	.005	36	view →
LGG	OS	Tertile	All	0.944	0.872	.003	18	view →
HNSC	DFS	Tertile	IV	0.529	0.299	.022	9	view →
LIHC	DFS	Tertile	All	1.000	0.284	.043	9	view →
SKCM	DFS	Tertile	All	0.856	0.617	.038	3	view →
KIRP	DFS	Tertile	III,IV	0.864	0.334	.047	3	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

CARS1P1–READ (DFS)

Open the READ breakdown →