CARNMT1

Across TCGA cell cohorts, CARNMT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,328 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CARNMT1-associated GO terms across cancer lineages are Positive regulation of mRNA 3'-end processing, Regulation of G2/M transition of mitotic cell cycle, and Regulation of centriole replication. Each is linked with CARNMT1 in more than 11 cancer types. Because this analysis shows association rather than direction, both CARNMT1-to-partner and partner-to-CARNMT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mRNA 3'-end processing grouped by CARNMT1-low versus CARNMT1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CARNMT1→partner) and Y-score (partner→CARNMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of mRNA 3'-end processing →	+0.132	+0.686	<.001	.006	3	12
LIVER	Regulation of G2/M transition of mitotic cell cycle →	+0.060	+0.642	<.001	<.001	3	11
BLOOD_Lymphoma	Regulation of centriole replication →	+0.073	+0.963	<.001	<.001	3	11
BREAST	Positive regulation of centriole replication →	+0.082	+0.653	<.001	<.001	3	10
LIVER	Positive regulation of mRNA processing →	+0.130	+0.606	.001	<.001	3	10
SKIN	Imidazole-containing compound catabolic process →	+0.890	+0.735	.003	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,328 associations by consensus.

Positive regulation of mRNA 3'-end processing by CARNMT1 expression — PANCREAS

Explore this box plot interactively →