CARNMT1

Across TCGA cell cohorts, CARNMT1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CARNMT1-associated genes across cancer lineages are ACTL9, MMP26, and GSG1L2. Each is linked with CARNMT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CARNMT1-to-partner and partner-to-CARNMT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACTL9 grouped by CARNMT1-low versus CARNMT1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CARNMT1→partner) and Y-score (partner→CARNMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ACTL9 →	+0.033	+6.022	<.001	.001	3	1
LARGE_INTESTINE	MMP26 →	+0.033	+3.217	<.001	.006	3	1
LARGE_INTESTINE	GSG1L2 →	+0.011	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ACTL9 by CARNMT1 expression — SKIN

Explore this box plot interactively →