Across TCGA pan-cancer cohorts, CARNMT1-AS1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated CARNMT1-AS1 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher CARNMT1-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated CARNMT1-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and HNSC show a favorable association.

UCS, HNSC, and ACC are the cancer types where CARNMT1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Median	II,III,IV	0.693	0.208	<.001	94	view →
HNSC	OS	Tertile	IV	0.679	0.335	.002	71	view →
ACC	DFS	Median	All	0.504	0.811	<.001	67	view →
THCA	DFS	Tertile	IV	0.717	1.000	.003	55	view →
LIHC	DFS	Quartile	All	0.429	0.591	.001	55	view →
UVM	DFS	Tertile	III,IV	0.261	0.813	.003	32	view →
BRCA	OS	Median	IV	0.564	0.179	.005	29	view →
KIRC	DFS	Quartile	IV	0.175	0.501	.008	24	view →
UCEC	DFS	Median	IV	0.750	0.372	.008	20	view →
THYM	OS	Median	II,III,IV	0.922	0.728	.017	15	view →
LUSC	OS	Median	All	0.807	0.711	.005	13	view →
READ	OS	Quartile	All	1.000	0.311	.010	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

Exploration

Same gene, other analysis: CARNMT1-AS1 tumor-vs-normal RNA expression · all CARNMT1-AS1 data types