CARMN

Across TCGA pan-cancer cohorts, CARMN RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated CARMN data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher CARMN RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CARMN expression acts as an unfavorable survival marker, although some lineages such as LIHC and HNSC show a favorable association.

KIRP, UVM, and BLCA are the cancer types where CARMN RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	All	0.517	0.791	<.001	104	view →
UVM	DFS	Tertile	All	0.389	0.792	<.001	101	view →
BLCA	OS	Median	All	0.349	0.497	.003	41	view →
LIHC	OS	Tertile	II,III,IV	0.598	0.235	.001	22	view →
HNSC	DFS	Quartile	IV	0.579	0.394	.007	19	view →
LUSC	DFS	Tertile	II,III,IV	0.323	0.477	.011	15	view →
COAD	DFS	Quartile	IV	0.346	0.586	.019	12	view →
THCA	DFS	Median	IV	1.000	0.525	.002	11	view →
READ	DFS	Tertile	III,IV	0.332	0.709	.010	9	view →
KIRC	DFS	Quartile	IV	0.402	0.665	.025	6	view →
LUAD	OS	Median	II,III,IV	0.560	0.348	.011	6	view →
BRCA	OS	Median	III,IV	0.611	0.458	.033	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

CARMN–KIRP (OS)

Open the KIRP breakdown →