Across TCGA patient cohorts, CARMIL3 mutation is significantly associated with the RNA expression of many other genes, with 3,732 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CARMIL3-associated genes across cancer lineages are BUB3, PBK, and WDHD1. Each is linked with CARMIL3 in more than 3 cancer types. Because this analysis shows association rather than direction, both CARMIL3-to-partner and partner-to-CARMIL3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CARMIL3→partner) and Y-score (partner→CARMIL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BUB3 →	+0.326	+1.338	<.001	.009	3	4
UCEC	PBK →	+0.563	+1.425	.001	<.001	3	4
COAD	WDHD1 →	+0.539	+1.947	.001	.009	3	4
UCEC	EXOSC9 →	+0.317	+1.667	.001	.001	3	4
GBM	SNORD111B →	+0.783	+5.554	<.001	<.001	3	3
CESC	YARS2 →	+0.511	+3.239	.003	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,732 associations by consensus.

Exploration

CARMIL3 survival (RNA) · tumor vs normal (RNA) · all CARMIL3 data types