CARMIL2

Across TCGA patient cohorts, CARMIL2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,285 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CARMIL2-associated genes across cancer lineages are PPP1R16B, ZAP70, and GZMB. Each is linked with CARMIL2 in more than 5 cancer types. Because this analysis shows association rather than direction, both CARMIL2-to-partner and partner-to-CARMIL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CARMIL2 versus PPP1R16B in GBM, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CARMIL2→partner) and Y-score (partner→CARMIL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PPP1R16B →	+1.619	+0.791	<.001	<.001	3	6
HNSC	ZAP70 →	+1.078	+0.441	.001	<.001	3	6
BRCA	GZMB →	+1.799	+0.409	<.001	.001	3	5
BRCA	SLA2 →	+0.921	+0.447	.001	.004	3	5
BRCA	POU2AF1 →	+1.152	+0.538	.001	<.001	3	5
BRCA	SLAMF1 →	+0.862	+0.508	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,285 associations by consensus.

CARMIL2 vs PPP1R16B — GBM

Explore this scatter interactively →