CARMIL2

Across TCGA cell cohorts, CARMIL2 mutation is significantly associated with the mutation status of many other genes, with 3,697 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CARMIL2-associated genes across cancer lineages are ROR2, WDR90, and DNAH10. Each is linked with CARMIL2 in more than 4 cancer types. Because this analysis shows association rather than direction, both CARMIL2-to-partner and partner-to-CARMIL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ROR2 grouped by CARMIL2-low versus CARMIL2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CARMIL2→partner) and Y-score (partner→CARMIL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ROR2 →	+3.697	+2.997	<.001	<.001	1	5
BLOOD_Leukemia	WDR90 →	+2.086	+2.225	.004	.004	1	5
BLOOD_Leukemia	DNAH10 →	+2.130	+2.818	<.001	<.001	1	5
SKIN	ATP2B4 →	+2.514	+2.807	.007	.007	1	5
LARGE_INTESTINE	TTC31 →	+3.287	+2.029	<.001	<.001	1	5
LARGE_INTESTINE	TRPC4 →	+1.842	+1.655	.004	.004	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,697 associations by consensus.

ROR2 by CARMIL2 expression — BLOOD_Leukemia

Explore this box plot interactively →