CARMAL

Across TCGA patient cohorts, CARMAL RNA expression is significantly associated with the protein abundance of many other proteins, with 10,478 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CARMAL-associated proteins across cancer lineages are SRPX, RCN3, and THBS2. Each is linked with CARMAL in more than 7 cancer types. Because this analysis shows association rather than direction, both CARMAL-to-partner and partner-to-CARMAL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CARMAL versus SRPX in CCRCC, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CARMAL→partner) and Y-score (partner→CARMAL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SRPX →	+1.380	+0.504	.007	.005	3	8
BRCA	RCN3 →	+0.661	+0.346	<.001	.009	3	7
CCRCC	THBS2 →	+1.655	+0.383	<.001	<.001	3	7
BRCA	CNN2 →	+0.804	+0.392	<.001	.001	3	6
CCRCC	EMILIN1 →	+0.523	+0.239	<.001	<.001	3	6
BRCA	HSPG2 →	+0.768	+0.584	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,478 associations by consensus.

CARMAL vs SRPX — CCRCC

Explore this scatter interactively →