CARM1

Across TCGA cell cohorts, CARM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,629 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible CARM1-associated GO terms across cancer lineages are Negative regulation of dendrite development, Positive regulation of anaphase-promoting complex-dependent catabolic process, and XMP metabolic process. Each is linked with CARM1 in more than 13 cancer types. Because this analysis shows association rather than direction, both CARM1-to-partner and partner-to-CARM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of dendrite development grouped by CARM1-low versus CARM1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CARM1→partner) and Y-score (partner→CARM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of dendrite development →	+0.264	+1.252	.003	.005	3	14
KIDNEY	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.107	+0.906	.001	.002	3	13
LUNG_SCLC	XMP metabolic process →	+0.164	+0.746	<.001	<.001	3	13
LUNG_SCLC	XMP biosynthetic process →	+0.164	+0.746	<.001	<.001	3	13
LUNG_SCLC	'de novo' XMP biosynthetic process →	+0.164	+0.746	<.001	<.001	3	13
BONE	Nucleosome disassembly →	+0.161	+0.869	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,629 associations by consensus.

Negative regulation of dendrite development by CARM1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →