CARF

Across TCGA patient cohorts, CARF protein abundance is significantly associated with the RNA expression of many other genes, with 2,500 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CARF-associated genes across cancer lineages are LINC00685, CXCL2, and CREBL2. Each is linked with CARF in more than 2 cancer types. Because this analysis shows association rather than direction, both CARF-to-partner and partner-to-CARF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CARF versus LINC00685 in LSCC, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CARF→partner) and Y-score (partner→CARF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LINC00685 →	-0.914	-0.753	.001	<.001	3	3
HNSC	CXCL2 →	+2.436	+1.047	.009	<.001	3	3
CCRCC	CREBL2 →	+0.402	+0.751	<.001	.008	3	2
CCRCC	ALDH2 →	+0.742	+0.851	.004	<.001	3	2
CCRCC	AFF2 →	+0.669	+0.576	<.001	.005	3	2
LUAD	CFAP221 →	+0.868	+0.508	.006	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,500 associations by consensus.

CARF vs LINC00685 — LSCC

Explore this scatter interactively →