CARD8

Across TCGA patient cohorts, CARD8 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,736 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CARD8-associated proteins across cancer lineages are WIPF1, GIMAP4, and IL16. Each is linked with CARD8 in more than 7 cancer types. Because this analysis shows association rather than direction, both CARD8-to-partner and partner-to-CARD8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CARD8 versus WIPF1 in OV, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CARD8→partner) and Y-score (partner→CARD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	WIPF1 →	+0.537	+0.675	<.001	<.001	3	8
HNSC	GIMAP4 →	+0.684	+0.603	<.001	<.001	3	8
OV	IL16 →	+0.717	+0.693	<.001	<.001	3	8
COAD	SHMT2 →	-0.527	-0.441	<.001	<.001	3	7
HNSC	TBC1D2B →	+0.249	+0.551	<.001	<.001	3	7
OV	PPP1R12C →	+0.294	+0.713	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,736 associations by consensus.

CARD8 vs WIPF1 — OV

Explore this scatter interactively →