CARD8-AS1

Across TCGA pan-cancer cohorts, CARD8-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated CARD8-AS1 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CARD8-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated CARD8-AS1 expression acts as an unfavorable survival marker, although some lineages such as COAD and LUAD show a favorable association.

COAD, LUAD, and KIRC are the cancer types where CARD8-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Quartile	IV	0.877	0.172	<.001	59	view →
LUAD	DFS	Tertile	All	0.858	0.756	.001	57	view →
KIRC	DFS	Median	All	0.736	0.516	.001	54	view →
LGG	OS	Median	All	0.338	0.577	<.001	54	view →
UVM	DFS	Quartile	III,IV	0.182	0.825	.001	38	view →
LAML	DFS	Tertile	All	0.241	0.519	.003	30	view →
CHOL	DFS	Median	All	0.681	0.121	<.001	27	view →
UCEC	DFS	Quartile	All	0.581	0.781	.005	22	view →
HNSC	DFS	Median	IV	0.654	0.505	.015	20	view →
KIRP	DFS	Quartile	III,IV	0.486	0.849	.018	13	view →
STAD	DFS	Tertile	IV	0.276	0.623	.021	12	view →
SKCM	OS	Quartile	All	0.425	0.227	<.001	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

CARD8-AS1–COAD (OS)

Open the COAD breakdown →