CARD6

Across TCGA patient cohorts, CARD6 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,507 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CARD6-associated proteins across cancer lineages are ARPC5, ATAD2, and SERPINB1. Each is linked with CARD6 in more than 6 cancer types. Because this analysis shows association rather than direction, both CARD6-to-partner and partner-to-CARD6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CARD6 versus ARPC5 in GBM, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CARD6→partner) and Y-score (partner→CARD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ARPC5 →	+0.288	+0.718	<.001	<.001	3	7
LUAD	ATAD2 →	-0.523	-0.666	<.001	<.001	3	7
GBM	SERPINB1 →	+0.707	+0.886	<.001	<.001	3	7
GBM	TMOD3 →	+0.385	+0.856	<.001	<.001	3	7
COAD	TOP1 →	-0.369	-0.737	<.001	<.001	3	7
UCEC	UBTF_S484 →	-1.169	-0.856	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,507 associations by consensus.

CARD6 vs ARPC5 — GBM

Explore this scatter interactively →