CARD19

Across TCGA patient cohorts, CARD19 protein abundance is significantly associated with the RNA expression of many other genes, with 9,235 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CARD19-associated genes across cancer lineages are PAK1IP1, STMN1, and PIMREG. Each is linked with CARD19 in more than 3 cancer types. Because this analysis shows association rather than direction, both CARD19-to-partner and partner-to-CARD19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CARD19 versus PAK1IP1 in UCEC, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CARD19→partner) and Y-score (partner→CARD19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PAK1IP1 →	-0.626	-0.352	.005	.004	3	4
LUAD	STMN1 →	-0.713	-0.281	.003	.001	3	4
GBM	PIMREG →	-0.922	-0.250	.001	.005	3	4
BRCA	DNA2 →	-0.852	-0.388	<.001	<.001	3	4
UCEC	KIF15 →	-1.038	-0.369	<.001	<.001	3	4
UCEC	DDIAS →	-0.709	-0.270	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,235 associations by consensus.

CARD19 vs PAK1IP1 — UCEC

Explore this scatter interactively →