CARD19

Across TCGA cell cohorts, CARD19 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,219 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CARD19-associated GO terms across cancer lineages are Membrane raft organization, Regulation of release of cytochrome c from mitochondria, and Regulation of establishment of T cell polarity. Each is linked with CARD19 in more than 11 cancer types. Because this analysis shows association rather than direction, both CARD19-to-partner and partner-to-CARD19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Membrane raft organization grouped by CARD19-low versus CARD19-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CARD19→partner) and Y-score (partner→CARD19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Membrane raft organization →	+0.143	+1.059	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of release of cytochrome c from mitochondria →	+0.110	+0.944	.004	.002	3	10
LIVER	Regulation of establishment of T cell polarity →	+0.213	+1.304	.001	<.001	3	10
BONE	Mitochondrial transcription →	-0.101	-1.151	<.001	<.001	3	10
OVARY	Response to oscillatory fluid shear stress →	+0.112	+0.686	.001	.003	2	10
OVARY	Cellular response to oscillatory fluid shear stress →	+0.112	+0.686	.001	.003	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,219 associations by consensus.

Membrane raft organization by CARD19 expression — BONE

Explore this box plot interactively →