CARD17

Across TCGA patient cohorts, CARD17 protein abundance is significantly associated with the RNA expression of many other genes, with 3,706 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CARD17-associated genes across cancer lineages are SIX4, MYBL2, and ISYNA1. Each is linked with CARD17 in more than 1 cancer types. Because this analysis shows association rather than direction, both CARD17-to-partner and partner-to-CARD17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CARD17 versus SIX4 in HNSC, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CARD17→partner) and Y-score (partner→CARD17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SIX4 →	-1.101	-0.766	<.001	<.001	3	2
HNSC	MYBL2 →	-1.101	-0.737	.001	.001	3	2
HNSC	ISYNA1 →	-1.061	-0.835	.001	.001	3	2
LSCC	TMEM97 →	-1.116	-0.963	.001	.003	3	2
HNSC	STMN1 →	-0.920	-1.032	<.001	<.001	3	2
HNSC	EPCAM →	-1.771	-0.952	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,706 associations by consensus.

CARD17 vs SIX4 — HNSC

Explore this scatter interactively →