CARD17

Across TCGA cell cohorts, CARD17 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,212 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CARD17-associated GO terms across cancer lineages are Complement activation, lectin pathway, Regulation of tumor necrosis factor-mediated signaling pathway, and Response to topologically incorrect protein. Each is linked with CARD17 in more than 5 cancer types. Because this analysis shows association rather than direction, both CARD17-to-partner and partner-to-CARD17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Complement activation, lectin pathway grouped by CARD17-low versus CARD17-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CARD17→partner) and Y-score (partner→CARD17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Complement activation, lectin pathway →	+1.486	+0.091	<.001	.006	3	6
BLOOD_Lymphoma	Regulation of tumor necrosis factor-mediated signaling pathway →	+0.095	+1.153	<.001	<.001	3	5
BLOOD_Lymphoma	Response to topologically incorrect protein →	+0.060	+0.877	<.001	<.001	3	5
LARGE_INTESTINE	Complement activation, classical pathway →	+0.969	+0.026	.001	.008	3	5
BLOOD_Lymphoma	Kidney mesenchymal cell proliferation →	+0.242	+0.902	<.001	<.001	3	5
BLOOD_Lymphoma	Metanephric mesenchymal cell proliferation involved in metanephros development →	+0.242	+0.902	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,212 associations by consensus.

Complement activation, lectin pathway by CARD17 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →