Across TCGA cell cohorts, CARD16 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,669 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CARD16-associated GO terms across cancer lineages are Positive regulation of chromatin binding, Negative regulation of viral genome replication, and CD8-positive, alpha-beta T cell homeostasis. Each is linked with CARD16 in more than 12 cancer types. Because this analysis shows association rather than direction, both CARD16-to-partner and partner-to-CARD16 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CARD16→partner) and Y-score (partner→CARD16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of chromatin binding →	+0.243	+2.057	<.001	<.001	3	13
BREAST	Negative regulation of viral genome replication →	+0.159	+1.722	<.001	<.001	3	13
URINARY_TRACT	CD8-positive, alpha-beta T cell homeostasis →	+0.158	+2.064	<.001	.002	3	13
BREAST	Negative regulation of viral process →	+0.123	+1.721	<.001	<.001	3	12
BLOOD_Lymphoma	Pyroptotic inflammatory response →	+0.135	+2.097	<.001	<.001	3	12
SOFT_TISSUE	Antigen processing and presentation of peptide antigen via MHC class I →	+0.167	+3.002	.001	<.001	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,669 associations by consensus.

Exploration

CARD16 survival (RNA) · tumor vs normal (RNA) · all CARD16 data types