CAPZA3

Across TCGA patient cohorts, CAPZA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,035 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CAPZA3-associated GO terms across cancer lineages are Fatty acid beta-oxidation, Cellular response to indole-3-methanol, and Morphogenesis of embryonic epithelium. Each is linked with CAPZA3 in more than 6 cancer types. Because this analysis shows association rather than direction, both CAPZA3-to-partner and partner-to-CAPZA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fatty acid beta-oxidation grouped by CAPZA3-low versus CAPZA3-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPZA3→partner) and Y-score (partner→CAPZA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Fatty acid beta-oxidation →	+0.026	+0.333	<.001	.003	3	7
STAD	Cellular response to indole-3-methanol →	+0.052	+0.196	<.001	.004	3	6
TGCT	Morphogenesis of embryonic epithelium →	+0.027	+0.354	<.001	.001	2	7
PAAD	Eye pigmentation →	+0.051	+0.489	<.001	<.001	3	6
STAD	Retinoic acid receptor signaling pathway →	+0.043	+0.202	<.001	<.001	3	6
TGCT	Mitochondrial electron transport, NADH to ubiquinone →	+0.023	+0.334	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,035 associations by consensus.

Fatty acid beta-oxidation by CAPZA3 expression — TGCT

Explore this box plot interactively →