Across TCGA patient cohorts, CAPZA2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,304 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CAPZA2-associated genes across cancer lineages are ABCA8, ZEB1, and ABCA9. Each is linked with CAPZA2 in more than 6 cancer types. Because this analysis shows association rather than direction, both CAPZA2-to-partner and partner-to-CAPZA2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPZA2→partner) and Y-score (partner→CAPZA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ABCA8 →	+1.023	+0.274	<.001	<.001	3	7
UCEC	ZEB1 →	+0.676	+0.262	.005	<.001	3	7
HNSC	ABCA9 →	+0.814	+0.232	<.001	<.001	3	7
UCEC	LMOD1 →	+1.317	+0.219	<.001	<.001	3	7
BRCA	MAMDC2 →	+1.233	+0.221	<.001	<.001	3	7
BRCA	ZCCHC24 →	+1.095	+0.224	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,304 associations by consensus.

Exploration

CAPZA2 survival (RNA) · tumor vs normal (RNA) · all CAPZA2 data types