Across TCGA patient cohorts, CAPZA2 mutation is significantly associated with the RNA expression of many other genes, with 155 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAPZA2-associated genes across cancer lineages are RNA5SP325, LINC02559, and USP9YP15. Each is linked with CAPZA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CAPZA2-to-partner and partner-to-CAPZA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPZA2→partner) and Y-score (partner→CAPZA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNA5SP325 →	+0.344	+6.837	<.001	<.001	3	2
CESC	LINC02559 →	+1.780	+6.342	<.001	.001	3	2
KIRC	USP9YP15 →	+0.099	+8.025	<.001	.007	3	2
UCEC	LINC01072 →	+0.112	+2.351	.004	.006	3	2
BRCA	MIR6894 →	+0.568	+5.506	<.001	.005	3	1
CESC	LYZL1 →	+0.056	+5.418	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 155 associations by consensus.

Exploration

CAPZA2 survival (RNA) · tumor vs normal (RNA) · all CAPZA2 data types