CAPZA1P4

Across TCGA pan-cancer cohorts, CAPZA1P4 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated CAPZA1P4 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CAPZA1P4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CAPZA1P4 expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

KIRC, KICH, and THCA are the cancer types where CAPZA1P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.491	0.682	<.001	114	view →
KICH	DFS	Tertile	All	0.035	0.904	<.001	90	view →
THCA	OS	Tertile	IV	0.095	0.966	<.001	84	view →
LIHC	OS	Tertile	II,III,IV	0.059	0.772	<.001	45	view →
LGG	OS	Tertile	All	0.819	0.932	.001	30	view →
LUAD	OS	Tertile	III,IV	0.057	0.680	<.001	27	view →
COAD	DFS	Tertile	II,III,IV	0.280	0.668	.017	27	view →
TGCT	OS	Tertile	III,IV	0.501	1.000	.014	18	view →
STAD	DFS	Quartile	All	0.255	0.453	.024	18	view →
ACC	OS	Tertile	IV	0.327	0.633	.045	18	view →
DLBC	DFS	Quartile	III,IV	0.072	0.847	.014	15	view →
KIRP	DFS	Tertile	All	0.711	0.880	.018	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

CAPZA1P4–KIRC (OS)

Open the KIRC breakdown →