Across TCGA pan-cancer cohorts, CAPZA1P3 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of CAPZA1P3’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where CAPZA1P3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CAPZA1P3 is over-expressed in tumor.
COAD and LUAD are the cancer types where CAPZA1P3 tumor–normal differential expression is most reproducible.