CAPZA1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CAPZA1 protein abundance is significantly associated with the RNA expression of many other genes, with 20,904 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CAPZA1-associated genes across cancer lineages are SIT1, TRAT1, and TRAV9-2. Each is linked with CAPZA1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CAPZA1-to-partner and partner-to-CAPZA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAPZA1 versus SIT1 in UCEC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPZA1→partner) and Y-score (partner→CAPZA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSIT1 →+1.015+0.207<.001.00438
UCECTRAT1 →+0.739+0.158<.001.00538
UCECTRAV9-2 →+1.112+0.199<.001.00438
GBMATP8B4 →+0.708+0.289<.001<.00137
GBMIL21R →+1.008+0.340<.001<.00137
OVLY86 →+1.030+0.252.006<.00128
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,904 associations by consensus.

CAPZA1 vs SIT1 — UCEC

Per-sample scatter of CAPZA1 vs SIT1 in UCEC (Pearson r = 0.39).

Explore this scatter interactively →

Exploration