CAPZA1

Across TCGA patient cohorts, CAPZA1 protein abundance is significantly associated with the protein abundance of many other proteins, with 30,932 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CAPZA1-associated proteins across cancer lineages are SH3BGRL3, CAPZB, and CFL1. Each is linked with CAPZA1 in more than 9 cancer types. Because this analysis shows association rather than direction, both CAPZA1-to-partner and partner-to-CAPZA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAPZA1 versus SH3BGRL3 in PDAC, with a Pearson correlation of 0.86.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPZA1→partner) and Y-score (partner→CAPZA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SH3BGRL3 →	+0.822	+0.505	<.001	<.001	3	10
LSCC	CAPZB →	+0.292	+0.324	<.001	<.001	3	10
OV	CFL1 →	+0.463	+0.303	.001	<.001	3	10
GBM	ARPC1B →	+0.673	+0.381	<.001	<.001	3	10
PDAC	CAP1 →	+0.405	+0.457	<.001	<.001	3	10
OV	WDR1 →	+0.569	+0.349	<.001	<.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 30,932 associations by consensus.

CAPZA1 vs SH3BGRL3 — PDAC

Explore this scatter interactively →