CAPZA1

Across TCGA cell cohorts, CAPZA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,696 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CAPZA1-associated GO terms across cancer lineages are Zinc ion import into Golgi lumen, Telomeric 3' overhang formation, and Protein localization to kinetochore. Each is linked with CAPZA1 in more than 14 cancer types. Because this analysis shows association rather than direction, both CAPZA1-to-partner and partner-to-CAPZA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Zinc ion import into Golgi lumen grouped by CAPZA1-low versus CAPZA1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPZA1→partner) and Y-score (partner→CAPZA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Zinc ion import into Golgi lumen →	+0.147	+0.878	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Telomeric 3' overhang formation →	+0.138	+0.867	.003	.006	3	14
SKIN	Protein localization to kinetochore →	+0.122	+0.530	<.001	.002	3	13
SKIN	Protein localization to condensed chromosome →	+0.150	+0.625	<.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Positive regulation of centriole replication →	+0.093	+0.852	.002	<.001	3	11
STOMACH	Positive regulation of mRNA processing →	+0.103	+0.498	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,696 associations by consensus.

Zinc ion import into Golgi lumen by CAPZA1 expression — KIDNEY

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