CAPS2-AS1

Across TCGA pan-cancer cohorts, CAPS2-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated CAPS2-AS1 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher CAPS2-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated CAPS2-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and KIRP show a favorable association.

BRCA, KIRC, and DLBC are the cancer types where CAPS2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Tertile	All	0.673	0.535	<.001	82	view →
KIRC	DFS	Median	III,IV	0.369	0.564	.009	28	view →
DLBC	DFS	Tertile	III,IV	0.150	0.758	.007	26	view →
THYM	OS	Tertile	All	0.617	0.893	.009	18	view →
HNSC	DFS	Tertile	III,IV	0.296	0.538	.018	18	view →
LUAD	DFS	Quartile	II,III,IV	0.276	0.490	.006	15	view →
LIHC	OS	Tertile	II,III,IV	0.458	0.729	.004	12	view →
KIRP	DFS	Tertile	All	1.000	0.794	.009	10	view →
COAD	DFS	Tertile	IV	0.107	0.515	.005	9	view →
SKCM	DFS	Tertile	IV	0.061	0.513	.033	9	view →
READ	DFS	Tertile	IV	0.303	0.650	.019	9	view →
LAML	DFS	Median	All	0.667	0.469	.021	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

CAPS2-AS1–BRCA (OS)

Open the BRCA breakdown →