CAPRIN2

Across TCGA patient cohorts, CAPRIN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,394 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CAPRIN2-associated proteins across cancer lineages are BICD1, P4HA1, and PLCL2_S1113. Each is linked with CAPRIN2 in more than 4 cancer types. Because this analysis shows association rather than direction, both CAPRIN2-to-partner and partner-to-CAPRIN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAPRIN2 versus BICD1 in HNSC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPRIN2→partner) and Y-score (partner→CAPRIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	BICD1 →	+0.360	+0.642	.001	<.001	3	5
PDAC	P4HA1 →	+0.607	+0.840	<.001	<.001	3	4
LSCC	PLCL2_S1113 →	-0.519	-0.469	<.001	<.001	3	4
CCRCC	CLEC11A →	+0.465	+0.229	.004	.006	3	4
PDAC	COX4I1 →	-0.469	-0.750	<.001	.001	3	4
LSCC	DNM1L →	+0.190	+0.419	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,394 associations by consensus.

CAPRIN2 vs BICD1 — HNSC

Explore this scatter interactively →