CAPRIN2

Across TCGA patient cohorts, CAPRIN2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,059 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CAPRIN2-associated genes across cancer lineages are STON2, TMSB4XP2, and RPL7P10. Each is linked with CAPRIN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CAPRIN2-to-partner and partner-to-CAPRIN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAPRIN2 versus STON2 in BRCA, with a Pearson correlation of -0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPRIN2→partner) and Y-score (partner→CAPRIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	STON2 →	-2.254	-0.957	<.001	.004	3	2
BRCA	TMSB4XP2 →	+2.436	+0.917	.005	.001	3	2
BRCA	RPL7P10 →	+2.140	+0.948	.003	<.001	3	2
BRCA	MORF4 →	+1.955	+0.984	.001	<.001	3	2
PDAC	PNN →	-0.636	-1.925	.001	.006	3	2
BRCA	SALL4 →	+1.328	+0.951	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,059 associations by consensus.

CAPRIN2 vs STON2 — BRCA

Explore this scatter interactively →