CAPRIN2

Across TCGA patient cohorts, CAPRIN2 mutation is significantly associated with the RNA expression of many other genes, with 5,087 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAPRIN2-associated genes across cancer lineages are SMNDC1, PANK3, and ZNF850. Each is linked with CAPRIN2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CAPRIN2-to-partner and partner-to-CAPRIN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMNDC1 grouped by CAPRIN2-low versus CAPRIN2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPRIN2→partner) and Y-score (partner→CAPRIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SMNDC1 →	+0.544	+3.198	.009	.009	3	3
SKCM	PANK3 →	+0.861	+3.341	.003	.005	3	3
SKCM	ZNF850 →	+0.666	+3.353	.003	.005	3	3
STAD	RBMY2TP →	+0.782	+4.084	<.001	.005	3	3
UCEC	GUF1 →	+0.502	+2.373	<.001	<.001	3	3
UCEC	GPATCH11 →	+0.478	+2.373	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,087 associations by consensus.

SMNDC1 by CAPRIN2 expression — SKCM

Explore this box plot interactively →