CAPRIN2

Across TCGA cell cohorts, CAPRIN2 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Myeloma shows the largest number of these associations.

The most reproducible CAPRIN2-associated genes across cancer lineages are C3orf22, SERPINA7, and KRT85. Each is linked with CAPRIN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CAPRIN2-to-partner and partner-to-CAPRIN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C3orf22 grouped by CAPRIN2-low versus CAPRIN2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPRIN2→partner) and Y-score (partner→CAPRIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	C3orf22 →	+0.042	+3.906	<.001	.002	3	2
BLOOD_Myeloma	SERPINA7 →	+0.459	+4.807	<.001	.006	3	1
BLOOD_Myeloma	KRT85 →	+0.026	+4.807	<.001	.006	3	1
BLOOD_Myeloma	C1orf158 →	+0.053	+4.807	<.001	.006	3	1
CNS	CSHL1 →	+0.021	+4.169	<.001	.008	3	1
OVARY	FMR1NB →	+0.120	+3.309	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

C3orf22 by CAPRIN2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →