CAPRIN1

Across TCGA patient cohorts, CAPRIN1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,412 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CAPRIN1-associated genes across cancer lineages are KIF18A, S1PR1, and ZWINT. Each is linked with CAPRIN1 in more than 8 cancer types. Because this analysis shows association rather than direction, both CAPRIN1-to-partner and partner-to-CAPRIN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAPRIN1 versus KIF18A in UCEC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPRIN1→partner) and Y-score (partner→CAPRIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KIF18A →	+0.965	+0.241	<.001	<.001	3	9
CCRCC	S1PR1 →	-0.949	-0.197	<.001	<.001	3	8
UCEC	ZWINT →	+1.453	+0.235	<.001	<.001	3	7
UCEC	NAT10 →	+0.736	+0.217	<.001	<.001	3	7
OV	PTH1R →	-0.942	-0.264	.004	.004	3	7
UCEC	CIP2A →	+0.975	+0.222	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,412 associations by consensus.

CAPRIN1 vs KIF18A — UCEC

Explore this scatter interactively →