CAPRIN1

Across TCGA patient cohorts, CAPRIN1 mutation is significantly associated with the RNA expression of many other genes, with 1,044 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAPRIN1-associated genes across cancer lineages are LINC02195, RPS3AP1, and RN7SL134P. Each is linked with CAPRIN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CAPRIN1-to-partner and partner-to-CAPRIN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02195 grouped by CAPRIN1-low versus CAPRIN1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPRIN1→partner) and Y-score (partner→CAPRIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LINC02195 →	+0.941	+3.335	<.001	.005	3	3
COAD	RPS3AP1 →	+0.181	+3.101	<.001	.008	3	3
UCEC	RN7SL134P →	+0.119	+2.014	<.001	.006	3	3
SKCM	OR4H12P →	+0.015	+4.351	<.001	.004	3	2
SKCM	LSMEM2 →	+0.323	+3.228	.001	.009	3	2
SKCM	RNU6-1285P →	+0.379	+2.631	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,044 associations by consensus.

LINC02195 by CAPRIN1 expression — COAD

Explore this box plot interactively →