CAPRIN1

Across TCGA cell cohorts, CAPRIN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,042 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CAPRIN1-associated GO terms across cancer lineages are Pyruvate decarboxylation to acetyl-CoA, Nucleic acid transport, and RNA transport. Each is linked with CAPRIN1 in more than 12 cancer types. Because this analysis shows association rather than direction, both CAPRIN1-to-partner and partner-to-CAPRIN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pyruvate decarboxylation to acetyl-CoA grouped by CAPRIN1-low versus CAPRIN1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPRIN1→partner) and Y-score (partner→CAPRIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Pyruvate decarboxylation to acetyl-CoA →	+0.150	+0.706	.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Nucleic acid transport →	+0.101	+0.763	.003	.001	3	13
UPPER_AERODIGESTIVE_TRACT	RNA transport →	+0.101	+0.763	.003	.001	3	13
BLOOD_Myeloma	Positive regulation of mRNA processing →	+0.108	+0.662	.004	.009	3	12
BLOOD_Lymphoma	Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery →	+0.127	+0.865	<.001	<.001	3	12
BONE	Negative regulation of DNA repair →	+0.080	+0.899	.008	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,042 associations by consensus.

Pyruvate decarboxylation to acetyl-CoA by CAPRIN1 expression — LUNG_SCLC

Explore this box plot interactively →