CAPNS2

Across TCGA cell cohorts, CAPNS2 mutation is significantly associated with the mutation status of many other genes, with 1,551 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible CAPNS2-associated genes across cancer lineages are PRELP, ZNF224, and ORAI1. Each is linked with CAPNS2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CAPNS2-to-partner and partner-to-CAPNS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRELP grouped by CAPNS2-low versus CAPNS2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPNS2→partner) and Y-score (partner→CAPNS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	PRELP →	+5.824	+5.824	.002	.002	1	3
OVARY	ZNF224 →	+5.415	+5.415	.004	.004	1	2
BLOOD_Leukemia	ORAI1 →	+4.321	+5.285	.005	.005	1	2
BLOOD_Leukemia	SRCIN1 →	+4.736	+5.560	.003	.003	1	2
OVARY	GGT5 →	+4.415	+4.977	.007	.007	1	2
BLOOD_Leukemia	KLHL24 →	+4.000	+5.050	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,551 associations by consensus.

PRELP by CAPNS2 expression — SKIN

Explore this box plot interactively →