CAPNS1

Across TCGA patient cohorts, CAPNS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,156 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CAPNS1-associated GO terms across cancer lineages are Regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, Autophagy of peroxisome, and Protein polyufmylation. Each is linked with CAPNS1 in more than 19 cancer types. Because this analysis shows association rather than direction, both CAPNS1-to-partner and partner-to-CAPNS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay grouped by CAPNS1-low versus CAPNS1-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPNS1→partner) and Y-score (partner→CAPNS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	-0.041	-0.359	<.001	<.001	3	20
UVM	Autophagy of peroxisome →	-0.053	-0.465	<.001	<.001	3	19
CHOL	Protein polyufmylation →	-0.083	-0.726	.002	.001	3	19
ESCA	Peptidyl-serine autophosphorylation →	-0.067	-0.371	<.001	<.001	3	19
THYM	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	-0.052	-0.269	<.001	<.001	3	19
CHOL	Protein ufmylation →	-0.075	-0.675	.002	.003	1	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,156 associations by consensus.

Regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay by CAPNS1 expression — THYM

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