CAPNS1

Across TCGA patient cohorts, CAPNS1 mutation is significantly associated with the RNA expression of many other genes, with 362 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAPNS1-associated genes across cancer lineages are RNU6-572P, RNU4-83P, and RPS28P1. Each is linked with CAPNS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CAPNS1-to-partner and partner-to-CAPNS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-572P grouped by CAPNS1-low versus CAPNS1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPNS1→partner) and Y-score (partner→CAPNS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-572P →	+0.442	+7.741	<.001	.009	3	2
UCEC	RNU4-83P →	+0.116	+5.365	<.001	<.001	3	2
UCEC	RPS28P1 →	+0.111	+3.027	<.001	.007	3	1
UCEC	RNU6-88P →	+0.656	+3.286	.009	.008	3	1
UCEC	H2BC6 →	-0.681	-3.403	.007	.005	3	1
UCEC	TRBV12-3 →	+0.503	+3.491	.003	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 362 associations by consensus.

RNU6-572P by CAPNS1 expression — COAD

Explore this box plot interactively →