CAPN9

Across TCGA patient cohorts, CAPN9 protein abundance is significantly associated with the RNA expression of many other genes, with 6,674 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CAPN9-associated genes across cancer lineages are VSIG2, MLPH, and AGR2. Each is linked with CAPN9 in more than 4 cancer types. Because this analysis shows association rather than direction, both CAPN9-to-partner and partner-to-CAPN9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAPN9 versus VSIG2 in BRCA, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN9→partner) and Y-score (partner→CAPN9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	VSIG2 →	+2.073	+1.082	.003	.007	3	5
COAD	MLPH →	+1.158	+0.632	.002	.001	3	4
COAD	AGR2 →	+1.376	+0.576	.004	.003	3	3
PDAC	SLC9A2 →	+1.207	+0.826	<.001	<.001	3	3
COAD	SCGB2A1 →	+1.268	+0.578	<.001	.001	3	3
LSCC	ATP13A4 →	+1.024	+0.346	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,674 associations by consensus.

CAPN9 vs VSIG2 — BRCA

Explore this scatter interactively →